Clinical therapeutics
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Clinical therapeutics · Jan 2004
ReviewSecondary osteoporosis: underlying disease and the risk for glucocorticoid-induced osteoporosis.
Chronic diseases of many organ systems require long-term (>or=1 year) treatment with glucocorticoids. Owing to the catabolic activity of glucocorticoid therapy, osteoporosis is a potential complication. ⋯ Men and women initiating long-term glucocorticoid treatment and those with GIO should be concomitantly treated with effective osteoporosis therapy to reduce fracture risk and counseled on preventive lifestyle changes.