Alcoholism, clinical and experimental research
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Alcohol. Clin. Exp. Res. · Jan 2004
Comparative StudyEndogenous opioid receptor genes and alcohol dependence among Taiwanese Han.
Nonselective opioid antagonists reduce alcohol consumption under various experimental situations, and several association studies have examined possible roles of opioid receptor mu (OPRM), delta (OPRD), and kappa (OPRK) genes in the development of alcohol dependence. ⋯ Our findings do not support a possible role of the opioid receptor genes for the proclivity to alcohol dependence in the Taiwanese Han.