Annals of neurology
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Annals of neurology · May 2015
Randomized Controlled Trial Multicenter StudyUric acid improves glucose-driven oxidative stress in human ischemic stroke.
A study was undertaken to test in a subgroup reanalysis of the URICO-ICTUS trial whether uric acid is superior to placebo in improving the functional outcome in patients with acute stroke and hyperglycemia. ⋯ Uric acid therapy was associated with reduced infarct growth and improved outcome in patients with hyperglycemia during acute stroke.