Pathologie-biologie
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Pathologie-biologie · May 1987
[In vitro study of the combination of pefloxacin with other antibiotics against Pseudomonas aeruginosa and Streptococcus group D].
The comparative susceptibility of 50 isolates of enterococci and 50 isolates of Pseudomonas aeruginosa to pefloxacin and different antibiotics was tested using MIC determination. The results showed only 6% sensitive strains of enterococci and 36% of P. aeruginosa. ⋯ The activity of the combination of pefloxacin and other antibiotics was determined by a checkerboard micromethod. Fractional concentration index (FIC and FBC) show most frequently addition, uncommonly synergy.