Early human development
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Early human development · Jun 2011
High plasma cytokine levels, white matter injury and neurodevelopment of high risk preterm infants: assessment at two years.
Controversy exists regarding association of high levels of proinflammatory cytokines, neonatal morbidities and poor neurodevelopment outcome in very low birth weight infants. ⋯ There was no association of high cytokines plasma levels with poor neurodevelopment outcome at 22 to 24 months' corrected age, suggesting that elevations of plasma proinflammatory cytokines early in life do not play an important role in pathophysiology of brain injury in high risk preterm infants.