Early human development
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Early human development · Jan 2012
Long-term neurological outcome of term-born children treated with two or more anti-epileptic drugs during the neonatal period.
Neonatal seizures may persist despite treatment with multiple anti-epileptic drugs (AEDs). ⋯ In term-born infants with seizures that required two or more AEDs outcome was poorer if seizure control failed. The number of AEDs required to reach seizure control and seizure aetiology had limited prognostic value.
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Early human development · Jan 2012
Skin conductance measurements as pain assessment in newborn infants born at 22-27 weeks gestational age at different postnatal age.
To assess pain or stress in newborn infants submitted to intensive care is important but difficult, as different observational pain scales are not always reliable in premature infants. As an indicator of pain, skin conductance (SC) measurements have detected increased sweating in newborn infants >28 gestational age (GA) submitted to heel lancing. ⋯ Changes in SC could be detected in infants at <28+0 PNA and related to the combination of heel lancing and squeezing. A maturational development of the SC was observed in infants born <28 GA. SC seems to be able to differentiate between pain and discomfort.