Herz
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Controlled Clinical Trial
H-FABP, cardiovascular risk factors, and functional status in asymptomatic spinal cord injury patients.
This was a cross-sectional study in the setting of a rehabilitation hospital. ⋯ H-FABP is related to MetS and FAC status in asymptomatic SCI patients.
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Paradoxical embolization through the patent foramen ovale (PFO) is the major cause of most cryptogenic stroke cases. However, the presence of PFO may simply be an incidental finding in these patients, and endothelial dysfunction may be the underlying reason of ischemic stroke. The aim of this study was to compare the endothelial function of cryptogenic stroke patients according to the presence of PFO. ⋯ Endothelial dysfunction seems to play a more important role than PFO in the underlying mechanism of cryptogenic stroke.
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Sleep apnea can influence cardiac function, by which the development of heart failure is facilitated. Vice versa, chronic heart failure increases the risk for sleep apnea. Consequently, in patients with symptomatic chronic heart failure, sleep apnea is a frequent comorbidity occuring in up to 75% of cases. ⋯ Therefore, a screening of all heart failure patients for sleep apnea is mandatory. Currently, large studies are underway which investigate whether the treatment of sleep apnea, esp. central sleep apnea, will beneficially influence the clinical course of heart failure (SERVE-HF, ADVENT-HF). A new therapeutic approach for central sleep apnea is the phrenic nerve stimulation.