The Journal of clinical psychiatry
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Randomized Controlled Trial Clinical Trial
Should anxiety and insomnia influence antidepressant selection: a randomized comparison of fluoxetine and imipramine.
The more sedating antidepressants are often recommended for patients presenting with anxiety or insomnia. We examine whether baseline anxiety or insomnia symptoms (1) show differential response to fluoxetine or imipramine or (2) predict differences between drugs in overall clinical response or likelihood of medication discontinuation. ⋯ Among patients with moderate depression, baseline levels of insomnia or anxiety should not influence the choice of fluoxetine or imipramine as an initial antidepressant.
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Letter Case Reports
Delirium with manic symptoms induced by diet pills.