The Journal of clinical psychiatry
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The goal of this study was to examine the associations between specific anxiety disorders and the risk of major depressive disorder and to explore the role of various clinical characteristics of anxiety disorders in these relationships using a prospective, longitudinal design. ⋯ Our findings suggest that anxiety disorders are risk factors for the first onset of major depressive disorder. Although a number of clinical characteristics of anxiety disorders appear to play a role in the association between anxiety disorders and depression, severe impairment is the strongest predictor of major depressive disorder.
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Comment Letter Comparative Study
Acetaminophen preferable to ibuprofen for pretreatment of electroconvulsive therapy-induced headache.
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Comparative Study Clinical Trial
Risperidone in the treatment of delirium: results from a prospective open-label trial.
Effective treatment is necessary to reverse delirium and prevent potentially serious consequences. ⋯ Low-dose risperidone can improve cognitive and behavioral symptoms of delirium in medically ill patients.
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Anticonvulsants that act as ligands at alpha(2)delta subunits of voltage-gated calcium channels are proving to be novel treatments for chronic pain.