The Journal of clinical psychiatry
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Review Meta Analysis Comparative Study
Does randomized evidence support sertraline as first-line antidepressant for adults with acute major depression? A systematic review and meta-analysis.
Preliminary evidence suggested that sertraline might be slightly superior to other antidepressant medications in terms of efficacy. The aim of this study was to carry out a systematic review and meta-analysis to compare sertraline with any other antidepressant in the acute phase treatment of major depression at 8 weeks. ⋯ The results of this review suggest that sertraline may be a candidate as the initial choice of antidepressant for people with major depression.