The Journal of physiology
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The Journal of physiology · Mar 1974
The effects of pentobarbitone anaesthesia on the volume and composition of the extracellular fluid of dogs.
1. The effects of pentobarbitone sodium (Nembutal) anaesthesia in dogs on extracellular fluid and plasma volumes, plasma protein concentration, haematocrit and extracellular fluid electrolyte composition were measured.2. ⋯ Extracellular fluid volume did not alter significantly during six hours of anaesthesia, but the haematocrit and extracellular fluid potassium concentration showed an increase towards control values.4. The relevance of these findings to the interpretation of experiments carried out under pentobarbitone anaesthesia is noted.