Ophthalmology
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Randomized Controlled Trial Multicenter Study Clinical Trial
Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study.
To investigate the risk factors associated with visual field (VF) progression in the Advanced Glaucoma Intervention Study (AGIS) with pointwise linear regression (PLR) analysis of serial VFs. ⋯ Both increasing age and greater IOP fluctuation increase the odds of VF progression by 30% (for each 5-year increment in age and 1-mmHg increase in IOP fluctuation). The higher risk conferred by IOP fluctuation was consistently observed in eyes with and without a history of cataract extraction.