Ophthalmology
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The Singapore Corneal Transplant Study (SCTS) is a 16-year prospective study of 2100 consecutive corneal transplants performed between January 1991 and November 2006 in patients from Southeast Asia at a single tertiary center. The indications, complications, long-term survival rates, and risk factors for graft failure of penetrating keratoplasty (PK) performed in Asian eyes are reported. ⋯ The long-term outcome for optical indications in Asian eyes follows a trend in endothelium-related attrition similar to that seen in the West. Tectonic and therapeutic keratoplasty for corneal infections and perforation, however, constitute a significant proportion of corneal transplantation performed in Asia and carry a graver prognosis in terms of graft survival.