Ophthalmology
-
Randomized Controlled Trial Multicenter Study
Safety and Efficacy of Adalimumab in Patients with Noninfectious Uveitis in an Ongoing Open-Label Study: VISUAL III.
To evaluate safety and efficacy of adalimumab in patients with noninfectious intermediate, posterior, or panuveitis. ⋯ Patients with active uveitis at study entry who received adalimumab therapy were likely to achieve quiescence, improve visual acuity, and reduce their daily uveitis-related systemic corticosteroid use. Most patients with inactive uveitis at study entry sustained quiescence without a systemic corticosteroid dose increase. No new safety signals were identified.