Drug development and industrial pharmacy
-
Comparative Study
Evaluation of the tamper-resistant properties of biphasic immediate-release/extended-release oxycodone/acetaminophen tablets.
Abuse potential of extended-release (ER) opioid tablets increases if tampering causes rapid opioid release. ⋯ IR/ER OC/APAP tablets may have less potential for abuse involving tampering compared with IR OC/APAP tablets.