The International journal of artificial organs
-
Multicenter Study Comparative Study Clinical Trial
Patient and kidney survival by dialysis modality in critically ill patients with acute kidney injury.
Using a large, international cohort, we sought to determine the effect of initial technique of renal replacement therapy (RRT) on the outcome of acute renal failure (ARF) in the intensive care unit (ICU). We enrolled 1218 patients treated with continuous RRT (CRRT) or intermittent RRT (IRRT) for ARF in 54 ICUs in 23 countries. We obtained demographic, biochemical and clinical data and followed patients to either death or hospital discharge. ⋯ However, the choice of CRRT was a predictor of dialysis independence at hospital discharge among survivors (OR: 3.333, 95% CI: 1.845 - 6.024, p<0.0001). Further adjustment using a propensity score did not significantly change these results. We conclude that worldwide, the choice of CRRT as initial therapy is not a predictor of hospital survival or dialysis-free hospital survival but is an independent predictor of renal recovery among survivors.
-
Randomized Controlled Trial Comparative Study
A pilot randomized controlled crossover study comparing regional heparinization to regional citrate anticoagulation for continuous venovenous hemofiltration.
To evaluate the efficacy and safety of a regional heparinization and a regional citrate method of anticoagulation in CVVH. ⋯ Regional heparinization and regional citrate anticoagulation achieve similar circuit life in critically ill patients receiving CVVH.
-
This study investigated prevalence and correlates of anemia and uncontrolled anemia in chronic hemodialysis patients. ⋯ Anemia and uncontrolled anemia are more frequent in hemodialysis patients with shortterm dialysis, diseases other than HCKD, low BMI, and female gender. Gender effect was lower in elderly patients. Uncontrolled anemia was also associated with low serum albumin and calcium, suggesting that these parameters are indices of EPO resistance.