The International journal of artificial organs
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The use of helium-oxygen mixture (heliox) for ventilation has an advantage in patients with obstruction of the airways. The physical properties of helium enable an easier gas flow through the airways; this enables easier breathing for the patient when compared to standard ventilation of air. A high cost of heliox falls within the factors that limit the use of heliox in clinical practice. At present, heliox is administered by use of an open circuit. The aim of this study is to propose a way of heliox administration that reduces heliox consumption but does not affect the positive heliox effects upon the airway resistance. ⋯ The designed semi-closed circuit offers a potential benefit of heliox in patients with COPD exacerbation.