The American journal of medicine
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Thirty-six patients were admitted to an open study designed to evaluate the long-term efficacy of gliclazide in the treatment of type II diabetes mellitus. Results from 27 of these patients were analyzed at 36 months, 21 at 48 months, and 16 at 60 months of follow-up. An overall reduction in fasting and postprandial blood sugar was observed (p less than 0.001). ⋯ Body weight remained stable over a period of observation ranging from 36 to 60 months. The incidence of subsequent failure of oral treatment was 2% per annum. These results show that long-term treatment of type II diabetes with gliclazide leads to satisfactory results, with practically no side effects.
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Comparative Study
Comparison of efficacy of automatic implantable cardioverter defibrillator in patients older and younger than 65 years of age.
The efficacy of the automatic implantable cardioverter defibrillator (AICD) was compared in elderly patients and younger patients with life-threatening ventricular tachyarrhythmias. Clinical characteristics, surgical complications, and long-term survival rates were compared between the two age groups. ⋯ It is concluded that AICD is a very effective treatment for life-threatening ventricular tachyarrhythmias, and this benefit applies to elderly patients as well as younger patients.