The American journal of medicine
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Comparative Study
The net transfer of transplant organs across race, sex, age, and income.
To determine how sociodemographic characteristics influence both access to transplantation and organ donation. ⋯ The sociodemographic characteristics of persons who donate organs and those who benefit from organ transplantation differ markedly. Efforts to improve access and increase donation should address these differences.
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PRESENTING FEATURES: An 85-year-old black woman presented to the Osler Medical Service complaining of a pruritic, erythematous scaly rash that was on her right thigh and abdomen and that had been worsening over the prior 3 months. She also complained of increasing fatigue, decreased exercise tolerance, and a 5-lbs weight loss. There was no orthopnea, paroxysmal nocturnal dyspnea, fevers, chills, or night sweats. ⋯ A peripheral blood smear (Figure 2) showed numerous atypical lymphocytes with cerebriform nuclei. Peripheral blood flow cytometry showed the presence of a clonal population of T cells that expressed CD4 and CD5 but showed a loss of CD7. What is the diagnosis?
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Letter Case Reports
Prognostic importance of lymphopenia in West Nile encephalitis.
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Review
Availability of large-scale evidence on specific harms from systematic reviews of randomized trials.
To assess how frequently systematic reviews of randomized controlled trials convey large-scale evidence on specific, well-defined adverse events. ⋯ Systematic reviews can convey useful large-scale information on adverse events. Acknowledging the importance and difficulties of studying harms, reporting of adverse effects must be improved in both randomized trials and systematic reviews.