The American journal of medicine
-
Randomized Controlled Trial Multicenter Study Clinical Trial
Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study.
To evaluate the efficacy and safety of a combination analgesic tablet (37.5 mg tramadol/325 mg acetaminophen) for the treatment of fibromyalgia pain. ⋯ A tramadol/acetaminophen combination tablet was effective for the treatment of fibromyalgia pain without any serious adverse effects.
-
Randomized Controlled Trial Clinical Trial
Third heart sound and elevated jugular venous pressure as markers of the subsequent development of heart failure in patients with asymptomatic left ventricular dysfunction.
To determine the independent prognostic value of a third heart sound (S(3)) and elevated jugular venous pressure in patients with asymptomatic left ventricular dysfunction. ⋯ The physical examination provides prognostic information among patients with asymptomatic or minimally symptomatic left ventricular dysfunction.
-
To evaluate the predictors of and time taken for the translation of highly promising basic research into clinical experimentation and use. ⋯ Even the most promising findings of basic research take a long time to translate into clinical experimentation, and adoption in clinical practice is rare.