International journal of epidemiology
-
Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of methods for analysing cluster randomized trials: an example involving a factorial design.
Studies involving clustering effects are common, but there is little consistency in their analysis. Various analytical methods were compared for a factorial cluster randomized trial (CRT) of two primary care-based interventions designed to increase breast screening attendance. ⋯ Commonly used methods for the analysis of CRT can give divergent results. Simulation studies are needed to compare results from different methods in situations typical of cluster trials but when the true model parameters are known.