International journal of epidemiology
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Comparative Study
Birthweight outcomes among Asian American and Pacific Islander subgroups in the United States.
Information on birth outcome among the Asian and Pacific Islander populations in the US is limited. This report examines the risks of moderately low (MLBW) and very low birthweight (VLBW) among six Asian subgroups (Chinese, Japanese, Fillipinos, Asian Indians, Koreans, Vietnamese) and three Pacific Islander subgroups (Hawaiians, Guamanians, Samoans) as compared with non-Hispanic whites. ⋯ Marked heterogeneity in birthweight outcome was observed between Asian American and Pacific Islander subgroups. This heterogeneity was not related to traditional demographic risk factors. Additionally, risks of VLBW and MLBW were not always related. These findings suggests that the Asian American and Pacific Islander populations should not be aggregated into a single category, and that traditional measures of risk and birth outcome may not be valid for those groups.
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Cape Town is undergoing rapid urbanization. South African vital statistics have routinely been stratified by racial categories but intra-urban and peri-urban geographical variations have been neglected. ⋯ Routine mortality data are more informative if stratified by robust and readily available indicators of socio-economic status such as residential area and racial category. Place of residence may distinguish risk strata as well as racial category, but the latter is helpful within socioeconomically heterogeneous residential areas.
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Inguinal hemia repair is one of the most common operations undertaken in routine surgical practice. It generally carries a very low risk of major adverse sequelae. We analysed profiles, separately, for elective and emergency operations to report on the incidence and major adverse outcomes of inguinal hernia repair in a geographically defined population. ⋯ The lifetime 'risk' of inguinal hernia repair is high: at currently prevailing rates we estimate it at 27% for men and 3% for women. There is significant elevation of mortality after emergency operations. Elective repair of inguinal hernia should be undertaken soon after the diagnosis is made to minimize the risk of adverse outcomes.
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Clinical Trial Controlled Clinical Trial
Child mortality following standard, medium or high titre measles immunization in West Africa.
The World Health Organization (WHO) recommended the use of high titre measles vaccine in 1989. Subsequent long term follow-up of several trials yielded results suggesting higher mortality among children inoculated with medium and high titre vaccines compared to standard titre vaccines, although none of the individual trials found significant differences in mortality. ⋯ The combined analysis showed a decreased survival related to high titre measles vaccine compared with standard titre vaccines, though solely among females. As a result of these studies from West Africa and a study from Haiti, WHO has recommended that high titre measles vaccine no longer be used.
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In general, information on the causes of adult deaths in developing countries is scarce. More specifically, relatively little is known about the effect of HIV-1 associated disease on adult mortality in general populations. In this study we have used a verbal autopsy technique to ascertain whether adult deaths were associated with HIV-1 in a rural population with a prevalence of HIV-1 infection of 8%, and used HIV-1 antibody status to validate the verbal autopsy findings. ⋯ The results of this study suggest that verbal autopsy studies may assist in providing data on HIV-associated mortality in general populations and may be useful as surveillance tools.