Muscle & nerve
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Comparative Study
Comparison of analysis approaches for phase III clinical trials in amyotrophic lateral sclerosis.
In this study we explore several methods for incorporating survival information in the analysis of Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) scores. ⋯ The shared parameter model and rank-based approach can offer improvements in power over traditional approaches.
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In this study we aimed to demonstrate the distinctive features of dysphagia in patients with myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD). ⋯ Our findings reveal the differences in the distinctive features of dysphagia in DM1 and DMD. Adjustments in the diet of DMD patients in accordance with swallowing ability could be useful.