Pacing and clinical electrophysiology : PACE
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Pacing Clin Electrophysiol · Jun 2006
Atrioventricular delay optimization by doppler-derived left ventricular dP/dt improves 6-month outcome of resynchronized patients.
Atrioventricular (AV) interval optimization, ensuring the best filling and the abolishment of presystolic mitral regurgitation, is crucial for the efficacy of cardiac resynchronization therapy (CRT). The methods proposed to optimize AV delay have many limitations. The maximum left ventricular pressure derivative (LV dP/dt)--an index of cardiac performance--could provide a clue for AV optimization. DP/dt can be calculated by the Doppler curve of mitral regurgitation jet and it is related to micromanometer-derived dP/dt. ⋯ Doppler-derived dP/dt for AV delay optimization determines better functional class and LVEF at 6 months follow-up relative to an empiric AV delay program.