Cancer chemotherapy and pharmacology
-
Cancer Chemother. Pharmacol. · Oct 2002
Comparative StudySuperior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.
Although NSAIDs (nonsteroidal antiinflammatory drugs) appear to be effective in the prevention and treatment of prostate cancer, very little information exists on the comparative effects of common nonprescription NSAIDs. In the present investigation, we evaluated the effects of widely used nonprescription NSAIDs on human prostate cancer cells in vitro. ⋯ These observations support the use of ibuprofen in future in vivo studies and in clinical trials designed to test the effectiveness of NSAIDs against human prostate cancer.