Cancer chemotherapy and pharmacology
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Cancer Chemother. Pharmacol. · Jul 2018
Comparative StudyTiming is everything: intraperitoneal chemotherapy after primary or interval debulking surgery for advanced ovarian cancer.
To evaluate the outcomes of intraperitoneal chemotherapy (IP) compared with those of intravenous chemotherapy (IV) in patients with advanced ovarian cancer after neoadjuvant chemotherapy (NACT) and interval debulking surgery (IDS) or primary debulking surgery (PDS). ⋯ Although IP chemotherapy after PDS is associated with improved survival, IP therapy after NACT and IDS, despite high rates of completion, may not have the same degree of survival advantage over IV therapy.