Journal of endocrinological investigation
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J. Endocrinol. Invest. · Apr 2013
Clinical TrialEffect of diet-induced weight loss on inflammatory cytokines in obese women.
Obesity is associated with lowgrade systemic inflammation which has been linked to the increased risk of cardiovascular disease and Type 2 diabetes in obese patients. ⋯ Our study suggests that an improved body composition induced by restriction of energy intake is associated with favorable serum concentrations of IL-6 and IL-18 in obese women. However, the anti-inflammatory IL-10 is not affected by a moderate weight decrease.