The International journal of neuroscience

The most recent articles from: Int. J. Neurosci. November 2011

Int. J. Neurosci. · Nov 2011

Randomized Controlled Trial Multicenter Study Comparative Study

Immediate versus delayed switch from levodopa/carbidopa to levodopa/carbidopa/entacapone: effects on motor function and quality of life in patients with Parkinson's disease with end-of-dose wearing off.

Assess motor function and quality of life (QoL) in Parkinson's disease (PD) subjects with end-of-dose wearing off (EODWO), comparing immediate and delayed switch (IS, DEL) to levodopa/carbidopa/entacapone (LCE). ⋯ The IS provided greater motor improvement at week 4 and improved QoL at week 8.

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