Sleep
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Randomized Controlled Trial Multicenter Study Clinical Trial
A randomized, double blind, placebo-controlled multicenter trial comparing the effects of three doses of orally administered sodium oxybate with placebo for the treatment of narcolepsy.
To evaluate and compare the efficacy and safety of three doses of sodium oxybate and placebo for the treatment of narcolepsy symptoms. ⋯ Sodium oxybate significantly improved symptoms in patients with narcolepsy and was well tolerated.
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In adults, sleep apnea is worse when the patient is in the supine position. However, the relationship between sleep position and obstructive apnea in children is unknown. The objective of this study was to evaluate the relationship between obstructive apnea and body position during sleep in children. ⋯ Children with obstructive sleep apnea, in contrast to adults, breathe best when in the supine position.