Médecine et maladies infectieuses
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Multicenter Study
[Antifungal treatments of candidemia in non-neutropenic patients: evaluation of practice in intensive care units].
The authors had for objective to assess systemic antifungal treatment for candidemia in non-neutropenic patients, in intensive care units (ICU), and compare the results with French 2004 recommendations. ⋯ The main causes of non-compliance to recommendations were the use of fluconazole in patients previously exposed to azole agents, the use of caspofungin in hemodynamically unstable patients, and the absence of therapeutic desescalade.
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Antibiotic management teams (AMTs) are recommended, but they are rarely implemented in France and their activity seldom evaluated. ⋯ Two third of BSIs were not initially treated by appropriate AT, more often in nosocomial BSI. Recommendation provided by the AMT was followed in 93% of cases.