Journal of cardiovascular pharmacology
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J. Cardiovasc. Pharmacol. · Dec 2008
Randomized Controlled TrialProtective effect of ambroxol on pulmonary function after cardiopulmonary bypass.
To evaluate whether ambroxol administered orally during the perioperative period has a protective effect against postoperative pulmonary dysfunction in on-pump coronary artery bypass surgery. ⋯ In on-pump coronary artery bypass grafting, ambroxol improves postoperative PFTs and PaO2 levels without any significant clinical implication, and it exerts these effects possibly in ways other than surfactant modulation.
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J. Cardiovasc. Pharmacol. · Dec 2008
Ivabradine induces an increase in ventricular fibrillation threshold during acute myocardial ischemia: an experimental study.
Tachycardia often facilitates ischemic ventricular fibrillation (VF). ⋯ HR reduction and the decrease in myocardial damage induced by IVA protected against primary ischemic VF without altering myocardial contractility.