Journal of cardiovascular pharmacology
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J. Cardiovasc. Pharmacol. · Oct 2014
Meta AnalysisMeta-analysis of efficacy and safety of the new anticoagulants versus warfarin in patients with atrial fibrillation.
To assess the efficacy and safety of the new oral anticoagulants versus warfarin in patients with atrial fibrillation by the meta-analyses performed for 5 studies ARISTOTLE, ENGAGE AF-TIMI 48, RE-LY, ROCKET-AF, and J-ROCKET. ⋯ The new oral anticoagulants demonstrated promising alternatives to warfarin in prevention of stroke in patients with atrial fibrillation.