Journal of cardiovascular pharmacology
-
J. Cardiovasc. Pharmacol. · Jul 2016
Multicenter Study Observational StudyDoes antiarrhythmic drug during cardio-pulmonary resuscitation improve the one-month survival: The SOS-KANTO 2012 study.
Antiarrhythmic drugs (AAD) are often used for fatal ventricular arrhythmias during cardiopulmonary resuscitation (CPR). However, the efficacy of initial AAD administration during CPR in improving long-term prognosis remains unknown. This study retrospectively evaluated the effect of AAD administration during CPR on 1-month prognosis in the SOS-KANTO 2012 study population. ⋯ Significantly greater 1-month survival was observed in the AAD group compared with the non-AAD group. However, the effect of ADD on the likelihood of a favorable neurological outcome remains unclear. The findings of the present study may indicate a requirement for future randomized controlled trials evaluating the effect of ADD administration during CPR on long-term prognosis.