Digestive diseases and sciences
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Randomized Controlled Trial
Influence of intraluminal acidification on esophageal secondary peristalsis in humans.
Secondary peristalsis contributes to clearance of retained refluxate or material from the esophagus. ⋯ Our data show that acute esophageal acid infusion enhances sensitivity of distension-induced secondary peristalsis and enhances secondary peristaltic activity. The study supports the evidence of the presence of acid-sensitive afferents in the modulation of distension-induced secondary peristalsis in humans.