Clinical cardiology
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Clinical cardiology · Nov 2002
Randomized Controlled Trial Clinical TrialHyperhomocysteinemia and endothelial function in young subjects: effects of vitamin supplementation.
The relationship between hyperhomocysteinemia and cardiovascular disease has not been totally elucidated. ⋯ Mild hyperhomocysteinemia is not associated with endothelial dysfunction in young male subjects with no additional cardiovascular risk factors, and reduction of tHcy by vitamin supplementation does not modify EDD in this age group. In this sample, tHcy was more related to vitamin B12 than to folic acid status.