Clinical cardiology
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Clinical cardiology · May 2005
Comparative StudyPeripheral arterial disease, acute coronary syndromes, and early invasive management: the TACTICS TIMI 18 trial.
Patients with peripheral arterial disease (PAD) represent a high-risk patient subset in the setting of non-ST-segment elevation acute coronary syndromes (NSTE ACS). The efficacy and safety of early invasive management for such patients remains unclear. ⋯ Among patients with NSTE ACS and a history of PAD, early invasive management is well tolerated and accompanied by significant reductions in morbidity and mortality when compared with a more conservative, ischemia-driven approach.