Clinical cardiology
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Clinical cardiology · Jun 2010
ReviewLoop diuretic therapy in heart failure: the need for solid evidence on a fluid issue.
Heart failure (HF) is a common condition associated with substantial cost, morbidity, and mortality. Because results of clinical trials in the acute decompensated heart failure (ADHF) setting have been mostly neutral, loop diuretics remain the mainstay of treatment. ⋯ Loop diuretics still prove useful in HF treatment, but risk-benefit analysis of these agents in the treatment of ADHF requires a well-designed prospective study.