Clinical cardiology
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Clinical cardiology · Jun 2010
Review Meta AnalysisEfficacy and safety of intracoronary autologous bone marrow-derived cell transplantation in patients with acute myocardial infarction: insights from randomized controlled trials with 12 or more months follow-up.
Until now there was no systematic review concerning the chronic effects of intracoronary bone marrow-derived cell (BMC) transplantation in patients with acute myocardial infarction (MI). ⋯ Beneficial effects of intracoronary BMC transplantation could last more than 12 months in acute MI patients.
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Clinical cardiology · Jun 2010
ReviewLoop diuretic therapy in heart failure: the need for solid evidence on a fluid issue.
Heart failure (HF) is a common condition associated with substantial cost, morbidity, and mortality. Because results of clinical trials in the acute decompensated heart failure (ADHF) setting have been mostly neutral, loop diuretics remain the mainstay of treatment. ⋯ Loop diuretics still prove useful in HF treatment, but risk-benefit analysis of these agents in the treatment of ADHF requires a well-designed prospective study.