Clinical cardiology
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Clinical cardiology · Sep 2017
Randomized Controlled Trial Multicenter StudyPeripheral artery disease and risk of adverse outcomes in heart failure with preserved ejection fraction.
Peripheral artery disease (PAD) in heart failure with preserved ejection fraction (HFpEF) is associated with an increased mortality risk, but the risk of individual outcomes associated with PAD in this patient group is less clear. ⋯ PAD increases the risk for adverse outcomes in HFpEF and is associated with HF rehospitalization. Practitioners should be aware of the inherent risk associated with PAD in HFpEF.
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Clinical cardiology · Sep 2017
Multicenter Study Observational StudyOral anticoagulation management in patients with atrial fibrillation undergoing cardiac implantable electronic device implantation.
Oral anticoagulation (OAC) therapy is associated with increased periprocedural risks after cardiac implantable electronic device (CIED) implantation. Patterns of anticoagulation management involving non-vitamin K antagonist oral anticoagulants (NOACs) have not been characterized. ⋯ Management of anticoagulation among AF patients undergoing CIED implantation is highly variable, with OAC being interrupted in more than half of both warfarin- and NOAC-treated patients. Bleeding and stroke events were infrequent in both warfarin and NOAC-treated patients.