Journal of ethnopharmacology
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Genus Syringa, which belongs to Oleaceae family, contains 21 accepted species mainly distributed in Southeast Europe, Japan, China, Himalayas, etc. The various parts of Syringa species have been used as traditional Chinese herbal medicines for treatment of cough, myocardial ischemia, acute icteric hepatitis, diarrhea, conjunctivitis, bronchitis and other ailments. ⋯ The phytochemistry, pharmacology, traditional uses and clinical applications described in this article demonstrated that Syringa species possessed a huge number of activities and these findings will promote the further action mechanisms studies. However, fewer preclinical and clinical studies are focued on the pharmacokinetics of crudes extracts and conpounds from Syringa. The explored of new agents with Syringa species as ingredients may be limited. It points to the further in-depth investigations on pharmacokinetics as well as toxicological are essential in future for assessment the effectiveness and safety of drug.