The Thoracic and cardiovascular surgeon
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Thorac Cardiovasc Surg · Jun 1986
Randomized Controlled Trial Clinical TrialA qualitative analysis of pulsatile perfusion: effects on cortisol response to cardiopulmonary bypass surgery.
Continuous analysis of pressure waveform has enabled quantitative assessment of pulsatile perfusion in a series of 51 patients randomly allocated to "pulsatile" (N = 37) and "non-pulsatile" (N = 14) groups. Cortisol and hematocrit (PCV) were measured preoperatively, at 2 minutes and 30 minutes after the start of bypass and just prior to the end of bypass. ⋯ Multiple regression analysis of cortisol and change in cortisol with pulse pressure dp/dt and mean arterial pressure failed to show any correlation. We found a normal cortisol response to surgery irrespective of the quality of pulsation.