The Thoracic and cardiovascular surgeon
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Thorac Cardiovasc Surg · Apr 2020
Meta AnalysisTopical Use of Tranexamic Acid in Cardiac Surgery: A Meta-Analysis.
This meta-analysis was conducted to investigate the evidence for the efficacy and safety of intrapericardial tranexamic acid (TXA) in cardiac surgery. ⋯ Findings from this meta-analysis suggest that intrapericardial use of TXA in patients undergoing cardiac surgery can decrease postoperative bleeding without increasing the risk of postoperative seizures. Future large randomized, double-blind, controlled clinical trials are needed to confirm these promising findings.