Japanese journal of clinical oncology
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Primary mediastinal malignant germ cell tumors (GCTs) are rare and have a worse prognosis than their gonadal counterparts. Although multimodality treatment is a standard therapeutic strategy in mediastinal GCTs, the clinical implications of surgical intervention remain unclear. ⋯ Surgical intervention for mediastinal GCT may be needed to remove a chemotherapy-refractory tumor or to assess the pathological response to chemotherapy to determine the indications for further chemotherapy.
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Jpn. J. Clin. Oncol. · Jul 2004
Validation of the Functional Assessment of Cancer Therapy-General (FACT-G) scale for measuring the health-related quality of life in Korean women with breast cancer.
The Functional Assessment of Cancer Therapy-General (FACT-G) scale, which was developed and validated in the USA, is widely used to measure the health-related quality of life in cancer patients. The purpose of the present study was to empirically validate the FACT-G scale with Korean breast cancer patients. ⋯ The Korean version of the FACT-G scale was demonstrated as reliable and valid. Therefore, the scale can be used in research and clinical settings to assess the quality of life of Korean breast cancer patients.
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Jpn. J. Clin. Oncol. · Jul 2004
Efficacy of modest dose irradiation in combination with long-term endocrinal treatment for high-risk prostate cancer: a preliminary report.
Although radiotherapy in combination with endocrinal manipulation has been identified as an effective treatment for patients with high-risk prostate cancer, the optimal dose for locoregional control of prostate cancer in combination with hormonal therapy has not yet been determined. ⋯ This study, though preliminary due to a short-term follow-up period, reveals the possibility that modest doses of irradiation combined with long-term endocrinal treatment could be an effective means of achieving excellent local control of high-risk prostate cancer.