Japanese journal of clinical oncology
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Jpn. J. Clin. Oncol. · Nov 2006
Clinical outcome in gastrointestinal stromal tumor patients who interrupted imatinib after achieving stable disease or better response.
Imatinib has been found to be effective in the treatment of patients with gastrointestinal stromal tumors (GIST). We sought to evaluate the clinical outcome of imatinib interruption in GIST patients who had achieved stable disease (SD) or showed better response to imatinib therapy. ⋯ In GIST patients controlled with imatinib, treatment might be interrupted, at least temporarily, when clinically warranted.
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Jpn. J. Clin. Oncol. · Nov 2006
Characteristics of advantages of positron emission tomography over computed tomography for N-staging in lung cancer patients.
We analyzed the characteristics of advantages of positron emission tomography (PET) over computed tomography (CT) for N-staging in lung cancer patients. ⋯ For N-staging, PET was superior to CT for the following: (1) more accurate for N0, N2 and N3 diseases but not for N1; (2) lower frequency of false-positive in the upper mediastinal nodes; and (3) lower frequencies of false-negative in adenocarcinoma and false-positive in squamous cell carcinoma. Recognizing these advantages of PET could make the N-staging of lung cancer more accurate.