Neurological research
-
Neurological research · Dec 2014
Alteration in the lower limit of autoregulation with elevations in cephalic venous pressure.
Recent studies suggest that elevated intracranial pressure (ICP), created by hydrocephalus, can alter the lower limit of cerebrovascular autoregulation (LLA). Our objective in the present study was to determine if ICP elevation from cerebral venous outflow obstruction would result in comparable alterations in the LLA. ⋯ Elevated ICP from cephalic venous engorgement leads to an increase in the LLA. These findings suggest that pathologic processes resulting in cephalic venous outflow obstruction and intracranial venous congestion can acutely elevate ICP and may place the brain at risk for impaired cerebrovascular autoregulation.
-
Neurological research · Dec 2014
Randomized Controlled TrialNeurosurgical tactile discrimination training with haptic-based virtual reality simulation.
To determine if a computer-based simulation with haptic technology can help surgical trainees improve tactile discrimination using surgical instruments. ⋯ Virtual computer-based simulators with integrated haptic technology may improve tactile discrimination required for microsurgical technique.
-
Neurological research · Dec 2014
Clinical TrialGabapentin versus pregabalin in relieving early post-surgical neuropathic pain in patients after lumbar disc herniation surgery: a prospective clinical trial.
The roles of gabapentin and pregabalin are well established in the management of chronic neuropathic pain. Here, we investigated the effectiveness of pregabalin and gabapentin for treating acute neuropathic pain following lumbar discectomy. ⋯ Many patients may suffer from neuropathic pain in the early post-surgical period after lumbar discectomy. Gabapentin and pregabalin are anticonvulsant agents that may decrease perioperative central sensitization and early post-surgical neuropathic pain. Gabapentin and pregabalin effectively relieved neuropathic pain and prevented the conversion of acute pain to chronic pain at the 1-year follow-up after lumbar discectomy.
-
Neurological research · Dec 2014
Module modified acute physiology and chronic health evaluation II: predicting the mortality of neuro-critical disease.
This study aimed to conduct and assess a module modified acute physiology and chronic health evaluation (MM-APACHE) II model, based on disease categories modified-acute physiology and chronic health evaluation (DCM-APACHE) II model, in predicting mortality more accurately in neuro-intensive care units (N-ICUs). ⋯ The APACHE II severity of disease classification system cannot provide accurate prognosis for all kinds of the diseases. A MM-APACHE II model can accurately predict hospital mortality for cerebral infarction, intracranial hemorrhage, and neurologic infection patients in N-ICU.
-
Neurological research · Dec 2014
Morphological parameters related to ruptured aneurysm in the patient with multiple cerebral aneurysms (clinical investigation).
We evaluated the rupture risk of multiple cerebral aneurysms in aspects of various morphological parameters, and determined which parameter can be a reliable predictor as one aneurysm ruptured, and the others did not. ⋯ Several morphological parameters were investigated to predict a rupture in multiple cerebral aneurysms using 3D angiogram. The aspect ratio, size ratio type I, daughter sac, and parent-daughter angle were revealed as competent parameters.