Journal of affective disorders
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Neurocognitive functioning is well known to be affected after ECT. However quantified data about the severity of the cognitive impairment after ultrabrief pulse and brief pulse ECT are limited, which makes it hard to judge its clinical relevance. ⋯ Loss of autobiographical memory is still present between one and six months after unilateral brief pulse ECT. Ultrabrief pulse RUL ECT shows less decline in autobiographical memory. Other neurocognitive impairments after brief pulse RUL ECT seem to be transient.
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There is no voxel-based morphometry study for first-episode, drug-naïve and very late-onset panic disorder patients. Besides, differences of onset age might represent different clinical subgroups. Therefore we designed this study to investigate gray matter deficits in this subgroup of patients. ⋯ Fronto-temporo-insula gray matter deficits might represent the structural pathophysiology of first-episode, drug-naïve and very late-onset panic disorder.