Journal of the American Academy of Dermatology
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J. Am. Acad. Dermatol. · Dec 2004
Multicenter StudySensitivity and specificity of reflectance-mode confocal microscopy for in vivo diagnosis of basal cell carcinoma: a multicenter study.
The current standard diagnostic procedure for basal cell carcinoma (BCC) is histologic examination after invasive biopsy. Reflectance-mode confocal microscopy (RCM) offers noninvasive high-resolution imaging of human skin in vivo. ⋯ RCM offers a sensitive and specific tool for the noninvasive diagnosis of BCC in vivo.
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J. Am. Acad. Dermatol. · Dec 2004
Pruritus, pain, and small nerve fiber function in keloids: a controlled study.
Keloid scars can itch and hurt, but little is known about the characteristics of these symptoms in keloids. Because itch and pain are carried by small nerve fibers, abnormal function of these fibers could be an explanation for such phenomena. ⋯ Itch and pain are common presentations in keloids and are associated with abnormalities in small nerve fiber function, suggesting a small nerve fiber neuropathy.