Journal of the American Academy of Dermatology
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J. Am. Acad. Dermatol. · Apr 2010
ReviewSystematic review of the safety of topical corticosteroids in pregnancy.
Pregnant women may have skin conditions that require topical corticosteroids. However, little is known about their safety in pregnancy. ⋯ Currently limited and inconclusive data are unable to detect an association between topical corticosteroids and congenital abnormality, preterm delivery, or stillbirth. The current evidence shows no statistically significant difference between pregnant women who use and those who do not use topical corticosteroids. However, there does appear to be an association of very potent topical corticosteroids with low birthweight. Further cohort studies with comprehensive outcome measures, consideration of corticosteroid potency, dosage and indications, and a large sample size are needed.