Journal of the American Academy of Dermatology
-
J. Am. Acad. Dermatol. · Oct 2016
Comparative Study Observational StudyTrends in the diagnosis and clinical features of melanoma in situ (MIS) in US men and women: A prospective, observational study.
The incidence of melanoma in situ (MIS) is increasing, but little is known about its clinical and epidemiologic features. ⋯ We found epidemiologic and clinical differences for in situ and invasive melanomas, which support further examination into the variations in etiologic pathways. The lack of improvement in mortality despite the increase in detection of in situ relative to invasive lesions further highlights the need to improve invasive melanoma-specific clinical screening features.