Brain & development
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Brain & development · Jan 1984
Historical ArticleA quarter-century of the Japanese Society of Child Neurology.
The 25th Annual Meeting of the Japanese Society of Child Neurology held from July 7 until 9, 1983 marked the approach of a quarter of a century in the history of the Society. The Society was founded in July, 1961 and has now existed for a full 22 years with a total of 25 annual meetings held. ⋯ Apart from the annual general assembly, the Society's main activities include the publication of two official journals--"No To Hattatsu" and "Brain & Development" both bimonthly--the sponsorship of postgraduate seminars on child neurology every year and the organization of International Symposia on Developmental Disabilities on a biennial bases. This is a synopsis of the quarter-century history of our Society, with a tincture of a rather subjective, personal account, presenting the reasons that led to the foundation of the Society, the social background of the time, and the circumstances that surrounded the Society's foundation.
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Brain & development · Jan 1984
Amino acid metabolism in the brain with convulsive disorders. Part 3: Free amino acid patterns in cerebrospinal fluid in infants and children with convulsive disorders.
Free amino acid patterns of cerebrospinal fluid in infants and children with various types of convulsive disorders were compared with those in age-matched normal subjects. The total free amino levels in Lennox syndrome were higher than the normal values, and those in infantile spasms controlled by ACTH were higher than those in uncontrolled infantile spasms. ⋯ After the treatment, in tonic-clonic seizure, the levels of taurine, asparagine and glycine were increased, and in infantile spasms, those of asparagine, glutamine, glycine, alanine, phenylalanine, lysine and arginine were increased while that of taurine was decreased. These results suggest that each type of convulsive disorder shows the specific amino acid pattern, and the effects of anticonvulsants may be partially understood through the changes of the free amino acid patterns in the brain.